I can wholeheartedly say that I really loved staying here. My room was on the 50th floor and had stunning views of the south strip, including the Luxor pyramid, Mandalay Bay, and with the mountains. Vdara is a no-casino hotel, which I found to be a plus despite my intention to gamble. The lack of casino made for a more relaxed environment, and a far less crowded or muddled layout as far as the lobby was concerned. Accessing the strip (or neighbouring casinos at the connected Bellagio or Aria) was just a short walk away.
My room was brilliant (as was Mike and Erin's on the other side of the tower). I had three giant windows with automatic shades, a stunning view, a large bathroom with a separate shower and tub, a small kitchen and dining area, and a spacious sitting area. The room even had a cool doorbell and electronic do not disturb light. It was an extremely comfortable and quiet place to come back to after a long day and the bed was top-notch (even for a quick jump).
Vdara isn't really in the heart of the action, but that's kind of what made it for me. I still felt close to everything on the strip, but the location at the back of the City Center complex made the hotel feel more private. I also found the maid service to be particularly good. Every evening when I returned my razor and toiletries were nicely laid out for me on the vanity, and extra care was even taken to roll up my laptop chord or chargers when I left them out.
I'd stay here again if I weren't so intent on trying a different hotel each time I go to Las Vegas, but I can certainly say that despite lacking a novelty theme, Vdara easily out-shined past stays at Circus Circus, MGM Grand, Harrah's, and the Plaza downtown. It's a polished and posh hub just steps away from all of the chaos and energy that make Vegas so much fun.